Sex differences in the activity of γ-aminobutyric acidergic neurons in the rat hypothalamus

被引：30

作者：

Grattan, DR ^{[1
]}

Selmanoff, M ^{[1
]}

机构：

[1] Univ Maryland, Sch Med, Dept Physiol, Ctr Studies Reprod, Baltimore, MD 21201 USA

来源：

BRAIN RESEARCH | 1997年 / 775卷 / 1-2期

关键词：

GABA turnover; gonadal steroid; hypothalamus; ventromedial nucleus; medial preoptic nucleus; sexually dimorphic nucleus; rat;

D O I：

10.1016/S0006-8993(97)01069-X

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The rate of GABA turnover was determined in nine microdissected brain regions in adult male and female rats. In the medial preoptic nucleus (central aspect) and ventromedial nucleus (ventrolateral aspect) of the hypothalamus, areas involved in the regulation of gonadotropin secretion and sex behavior, GABAergic neuronal activity was about 2-fold greater in males than females. These results demonstrate a striking sexual dimorphism in the activity of specific populations of hypothalamic CABAergic neurons. (C) 1997 Elsevier Science B.V.

引用

页码：244 / 249

页数：6

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