Structures of redox enzymes

被引:11
作者
Munro, AW
Taylor, P
Walkinshaw, MD
机构
[1] Univ Strathclyde, Dept Pure & Appl Chem, Royal Coll, Glasgow G1 1XW, Lanark, Scotland
[2] Univ Strathclyde, Dept Biosci & Biotechnol, Royal Coll, Glasgow G1 1XW, Lanark, Scotland
[3] Univ Edinburgh, Inst Cell & Mol Biol, Struct Biochem Grp, Edinburgh EH9 3JR, Midlothian, Scotland
关键词
D O I
10.1016/S0958-1669(00)00112-9
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
There is an ever increasing flood of structural information and over 1000 protein structures have been deposited in the Protein Data Base between January 1999 and January 2000. Major advances in the past year in the field of redox enzymes have included the structures of nitric oxide synthases in ligand-free and ligand-bound complexes, and the determination of the multi-subunit mitochondrial bc(1) complex. The first structures of flavocytochrome have also appeared providing insight into novel electron and proton pathways.
引用
收藏
页码:369 / 376
页数:8
相关论文
共 35 条
[1]  
Bamford V, 1999, NAT STRUCT BIOL, V6, P1104
[2]   N-terminal domain swapping and metal ion binding in nitric oxide synthase dimerization [J].
Crane, BR ;
Rosenfeld, RJ ;
Arvai, AS ;
Ghosh, DK ;
Ghosh, S ;
Tainer, JA ;
Stuehr, DJ ;
Getzoff, ED .
EMBO JOURNAL, 1999, 18 (22) :6271-6281
[3]   The structure of nitric oxide synthase oxygenase domain and inhibitor complexes [J].
Crane, BR ;
Arvai, AS ;
Gachhui, R ;
Wu, CQ ;
Ghosh, DK ;
Getzoff, ED ;
Stuehr, DJ ;
Tainer, JA .
SCIENCE, 1997, 278 (5337) :425-431
[4]   Structure of nitric oxide synthase oxygenase dimer with pterin and substrate [J].
Crane, BR ;
Arvai, AS ;
Ghosh, DK ;
Wu, CQ ;
Getzoff, ED ;
Stuehr, DJ ;
Tainer, JA .
SCIENCE, 1998, 279 (5359) :2121-2126
[5]   Mechanism of ubiquinol oxidation by the bc1 complex:: Role of the iron sulfur protein and its mobility [J].
Crofts, AR ;
Guergova-Kuras, M ;
Huang, LS ;
Kuras, R ;
Zhang, ZL ;
Berry, EA .
BIOCHEMISTRY, 1999, 38 (48) :15791-15806
[6]   Structure of cytochrome c nitrite reductase [J].
Einsle, O ;
Messerschmidt, A ;
Stach, P ;
Bourenkov, GP ;
Bartunik, HD ;
Huber, R ;
Kroneck, PMH .
NATURE, 1999, 400 (6743) :476-480
[7]   Bacterial dehalogenation [J].
Fetzner, S .
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 1998, 50 (06) :633-657
[8]   Structural characterization of nitric oxide synthase isoforms reveals striking active-site conservation [J].
Fischmann, TO ;
Hruza, A ;
Niu, XD ;
Fossetta, JD ;
Lunn, CA ;
Dolphin, E ;
Prongay, AJ ;
Reichert, P ;
Lundell, DJ ;
Narula, SK ;
Weber, PC .
NATURE STRUCTURAL BIOLOGY, 1999, 6 (03) :233-242
[9]   Identification of the catalytic triad in the haloalkane dehalogenase from Sphingomonas paucimobilis UT26 [J].
Hynková, K ;
Nagata, Y ;
Takagi, M ;
Damborsky, J .
FEBS LETTERS, 1999, 446 (01) :177-181
[10]   Structure of the Escherichia coli fumarate reductase respiratory complex [J].
Iverson, TM ;
Luna-Chavez, C ;
Cecchini, G ;
Rees, DC .
SCIENCE, 1999, 284 (5422) :1961-1966