Phase I/II Study of Intrapleural Administration of a Serotype rh.10 Replication-Deficient Adeno-Associated Virus Gene Transfer Vector Expressing the Human α1-Antitrypsin cDNA to Individuals with α1-Antitrypsin Deficiency

被引：15

作者：

Chiuchiolo, Maria J. ^{[1
]}

Kaminsky, Stephen M. ^{[1
]}

Sondhi, Dolan ^{[1
]}

Mancenido, Denesy ^{[1
]}

Hollmann, Charleen ^{[1
]}

Crystal, Ronald G. ^{[1
]}

机构：

[1] Weill Cornell Med Coll, Dept Med Genet, New York, NY 10065 USA

来源：

HUMAN GENE THERAPY CLINICAL DEVELOPMENT | 2014年 / 25卷 / 03期

关键词：

HUMORAL IMMUNE-RESPONSES; T-LYMPHOCYTE RESPONSES; IN-VIVO; FACTOR-IX; SKELETAL-MUSCLE; CLINICAL-TRIAL; ALPHA(1)-ANTITRYPSIN DEFICIENCY; TRANSGENE EXPRESSION; AUGMENTATION THERAPY; ADENOVIRUS VECTOR;

D O I：

10.1089/humc.2014.2513

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

[No abstract available]

引用

页码：112 / 133

页数：22

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