Antifungal and larvicidal meroterpenoid naphthoquinones and a naphthoxirene from the roots of Cordia linnaei

被引：45

作者：

Ioset, JR

Marston, A

Gupta, MP

Hostettmann, K ^{[1
]}

机构：

[1] Univ Lausanne, Inst Pharmacognosie & Phytochim, BEP, CH-1015 Lausanne, Switzerland

[2] Univ Panama, Coll Pharm, Ctr Pharmacognost Res Panamanian Flora, CIFLORPAN, Panama City, Panama

来源：

PHYTOCHEMISTRY | 1998年 / 47卷 / 05期

关键词：

Cordia linnaei; Boraginaceae; naphthoquinones; antifungal activity; larvicidal activity;

D O I：

10.1016/S0031-9422(97)00695-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

Three new meroterpenoid naphthoquinones, the known cordiaquinone B and a new naphthoxirene have been isolated from the roots of Cordia linnaei. Their structures were established by spectrometric methods including EI, D/CI and FAB mass spectrometry, H-1, C-13 and 2D NMR experiments. The naphthoquinones showed activity against Cladosporium cucumerinum: Candida albicans and the larvae of the yellow fever-transmitting mosquito Aedes aegypti, while the naphthoxirene derivative was found to be inactive in the same bioassays. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：729 / 734

页数：6

共 15 条

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NAPHTHAQUINONES OF DIOSPYROS-BATOCANA [J].