Combined effects of smoking and hypercholesterolemia on inflammatory process, thrombosis/fibrinolysis system, and forearm hyperemic response

被引：28

作者：

Antoniades, C ^{[1
]}

Tousoulis, D ^{[1
]}

Vasiliadou, C ^{[1
]}

Marinou, K ^{[1
]}

Tentolouris, C ^{[1
]}

Ntarladimas, I ^{[1
]}

Stefanadis, C ^{[1
]}

机构：

[1] Univ Athens, Med Sch, Dept Cardiol, GR-10679 Athens, Greece

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 2004年 / 94卷 / 09期

关键词：

D O I：

10.1016/j.amjcard.2004.07.090

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The combined effects of smoking and hypercholesterolemia on the inflammatory process, the thrombosis/fibrinolysis system, and forearm hyperemic response were investigated. It was shown that smokers with hypercholesterolemia (n = 25) had a reduced and delayed forearm hyperemic response compared with healthy smokers (n = 24), patients with hypercholesterolemia (n 26), and healthy controls (n = 75; p < 0.01 for all). This phenomenon was associated with a respective increase in the inflammatory process and changes in the thrombosis/fibrinolysis system. (C) 2004 by Excerpta Medica, Inc.

引用

页码：1181 / 1184

页数：4

共 15 条

[1]

Aggoun Y, 2000, ARTERIOSCL THROM VAS, V20, P2070

[2]

Antoniades C, 2003, HERZ, V28, P628, DOI 10.1007/s00059-003-2417-8

[3] Rotation between markers of systemic vascular inflammation and smoking in women [J].

Bermudez, EA ;

Rifai, N ;

Buring, JE ;

Manson, JE ;

Ridker, PM .

AMERICAN JOURNAL OF CARDIOLOGY, 2002, 89 (09) :1117-+

[4] Interrelationships among circulating interleukin-6, C-reactive protein, and traditional cardiovascular risk factors in women [J].

Bermudez, EA ;

Rifai, N ;

Buring, J ;

Manson, JE ;

Ridker, PA .

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2002, 22 (10) :1668-1673

[5] CIGARETTE-SMOKING IS ASSOCIATED WITH DOSE-RELATED AND POTENTIALLY REVERSIBLE IMPAIRMENT OF ENDOTHELIUM-DEPENDENT DILATION IN HEALTHY-YOUNG ADULTS [J].

CELERMAJER, DS ;

SORENSEN, KE ;

GEORGAKOPOULOS, D ;

BULL, C ;

THOMAS, O ;

ROBINSON, J ;

DEANFIELD, JE .

CIRCULATION, 1993, 88 (05) :2149-2155

[6] Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) Final Report [J].

Grundy, SM ;

Becker, D ;

Clark, LT ;

Cooper, RS ;

Denke, MA ;

Howard, WJ ;

Hunninghake, DB ;

Illingworth, R ;

Luepker, RV ;

McBride, P ;

McKenney, JM ;

Pasternak, RC ;

Stone, NJ ;

Van Horn, L ;

Brewer, HB ;

Cleeman, JI ;

Ernst, ND ;

Gordon, D ;

Levy, D ;

Rifkind, B ;

Rossouw, JE ;

Savage, P ;

Haffner, SM ;

Orloff, DG ;

Proschan, MA ;

Schwartz, JS ;

Sempos, CT ;

Shero, ST ;

Murray, EZ ;

Keller, SA ;

Jehle, AJ .

CIRCULATION, 2002, 106 (25) :3143-3421

[7] Effect of vitamin E on endothelial vasodilator function in patients with hypercholesterolemia, chronic smoking or both [J].

Heitzer, T ;

Herttuala, SY ;

Wild, E ;

Luoma, J ;

Drexler, H .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1999, 33 (02) :499-505

[8] Effect of the angiotensin-converting enzyme inhibitor imidapril on reactive hyperemia in patients with essential hypertension: Relationship between treatment periods and resistance artery endothelial function [J].

Higashi, Y ;

Sasaki, S ;

Nakagawa, K ;

Matsuura, H ;

Kajiyama, G ;

Oshima, T .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2001, 37 (03) :863-870

[9] Converting enzyme inhibitor improves forearm reactive hyperemia in essential hypertension [J].

Iwatsubo, H ;

Nagano, M ;

Sakai, T ;

Kumamoto, K ;

Morita, R ;

Higaki, J ;

Ogihara, T ;

Hata, T .

HYPERTENSION, 1997, 29 (01) :286-290

[10] INCREASE IN CIRCULATING PRODUCTS OF LIPID-PEROXIDATION (F-2-ISOPROSTANES) IN SMOKERS - SMOKING AS A CAUSE OF OXIDATIVE DAMAGE [J].

MORROW, JD ;

FREI, B ;

LONGMIRE, AW ;

GAZIANO, JM ;

LYNCH, SM ;

SHYR, Y ;

STRAUSS, WE ;

OATES, JA ;

ROBERTS, LJ .

NEW ENGLAND JOURNAL OF MEDICINE, 1995, 332 (18) :1198-1203

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