In vitro activities of the glycylcycline GAR-936 against gram-positive bacteria

被引：89

作者：

Boucher, HW

Wennersten, CB

Eliopoulos, GM

机构：

[1] Beth Israel Deaconess Med Ctr, Dept Med, Boston, MA 02215 USA

[2] Harvard Univ, Sch Med, Boston, MA 02115 USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2000年 / 44卷 / 08期

关键词：

D O I：

10.1128/AAC.44.8.2225-2229.2000

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The in vitro activities of GAR-936, the 9-t-butylglycylamido derivative of minocycline, were compared with those of doxycycline, minocycline, acid tetracycline against 527 gram-positive clinical isolates. GAR-936 inhibited all strains, including those resistant to other tetracyclines, at concentrations of less than or equal to 2 mu g/ml, except two strains of JE; diphtheroids for which the MIC was 4 mu g/ml.

引用

页码：2225 / 2229

页数：5

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