The pixyl (Px) group: A novel photocleavable protecting group for primary alcohols

被引：27

作者：

Misetic, A ^{[1
]}

Boyd, MK ^{[1
]}

机构：

[1] Loyola Univ, Dept Chem, Chicago, IL 60626 USA

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 13期

关键词：

D O I：

10.1016/S0040-4039(98)00013-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The 9-phenylxanthyl (pixyl or Px) moiety has been investigated as a potential photocleavable protecting group for primary alcohols. Alcohols 2a-e were protected in good yield by treatment with 9-chloro-9-phenylxanthene in dry pyridine at room temperature. Irradiation of the alcohol derivatives in neutral aqueous acetonitrile regenerates 2a-e and the 9-phenylxanthyl alcohol. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：1653 / 1656

页数：4

共 12 条

[1]

[Anonymous], ORG PHOTOCHEM

[2] ADVANCES IN THE SYNTHESIS OF OLIGONUCLEOTIDES BY THE PHOSPHORAMIDITE APPROACH [J].