Selective photocleavage of single-stranded nucleic acids by cyclobisintercaland molecules

被引：10

作者：

Blacker, AJ

Teulade-Fichou, MP

Vigneron, JP

Fauquet, M

Lehn, JM

机构：

[1] Univ Strasbourg 1, ISIS, Lab Chim Supramol, F-67000 Strasbourg, France

[2] Coll France, CNRS UPR 285, Lab Chim Interact Mol, F-75005 Paris, France

[3] CHU Pitie Salpetriere, CNRS URA 2115, Lab Cytosquelette, F-75013 Paris, France

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1998年 / 8卷 / 06期

关键词：

D O I：

10.1016/S0960-894X(98)00085-7

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Irradiation of mixtures of a single-stranded circular plasmid and of a double-stranded supercoiled DNA in presence of the cyclobisintercaland compounds 2 or 3 shows that these reagents effect the selective photocleavage of the single-stranded entity. Furthermore, 2 also cleaves tRNAasp preferentially at single stranded domains. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：601 / 606

页数：6

共 23 条

[1]

[Anonymous], 1985, COMMENTS INORG CHEM

[2] PHOTOCHEMICAL CLEAVAGE OF DNA BY 2,7-DIAZAPYRENIUM CATIONS [J].