Analysis and design of three-stranded coiled coils and three-helix bundles

被引：57

作者：

Schneider, JP

Lombardi, A

DeGrado, WF ^{[1
]}

机构：

[1] Univ Penn, Dept Biochem & Biophys, Johnson Res Fdn, Philadelphia, PA 19104 USA

[2] Univ Naples Federico II, CNR, Ctr Studio Biocristallog, I-80134 Naples, Italy

[3] Univ Naples Federico II, CNR, Ctr Interdipartimentale Ric Peptidi Bioacttivi, I-80134 Naples, Italy

来源：

FOLDING & DESIGN | 1998年 / 3卷 / 02期

关键词：

D O I：

10.1016/S1359-0278(98)00011-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Three-stranded coiled coils and three-helix bundles are increasingly being identified in proteins. Design and engineering on the scaffolds of these motifs is a potential route towards combating associated viral infections as well as introducing novel functional sites.

引用

收藏

页码：R29 / R40

页数：12

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