Calcium, a signaling molecule in the endoplasmic reticulum?

被引：216

作者：

Corbett, EF ^{[1
]}

Michalak, M

机构：

[1] Univ Alberta, MRC, Grp Mol Biol Membranes, Edmonton, AB T6G 2H7, Canada

[2] Univ Alberta, Dept Biochem, Edmonton, AB T6G 2H7, Canada

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 2000年 / 25卷 / 07期

关键词：

D O I：

10.1016/S0968-0004(00)01588-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

For many years now, it has been known that Ca2+ is an important signaling molecule in the cytosol of the cell, but emerging evidence suggests that Ca2+ might also play a signaling role in the endoplasmic reticulum. For example, agonist-induced fluctuations in free Ca2+ concentration in the endoplasmic reticulum can affect many functions of the endoplasmic reticulum, including protein synthesis and modification, and interchaperone interactions.

引用

页码：307 / 311

页数：5

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