Antibiotic prophylaxis for post-operative wound infection in clean elective breast surgery

被引：72

作者：

Gupta, R

Sinnett, D

Carpenter, R

Preece, PE

Royle, GT ^{[1
]}

机构：

[1] Royal S Hants Hosp, Dept Surg, Southampton SO9 4PE, Hants, England

[2] Charing Cross Hosp, Dept Surg, London, England

[3] St Bartholomews Hosp, Dept Surg, London, England

[4] Univ Dundee, Ninewells Hosp & Med Sch, Dept Surg, Dundee DD1 9SY, Scotland

来源：

EUROPEAN JOURNAL OF SURGICAL ONCOLOGY | 2000年 / 26卷 / 04期

关键词：

antibiotic prophylaxis; post-operative infections;

D O I：

10.1053/ejso.1999.0899

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Antibiotic prophylaxis has been used to good effect in the prevention of post-operative wound infections in patients undergoing gastrointestinal operations. We have assessed the use of a single dose of intravenous antibiotic (Augmentin 1.2 g), given with induction of anaesthesia as prophylaxis, against post-operative wound infection in women undergoing clean, elective breast surgery. Three hundred and thirty-four patients were recruited. Of the 164 receiving antibiotic prophylaxis 29 (17.7%) had wound infections compared with 32 (18.8%) in the placebo group (P = 0.79). There were no significant differences in any other post-operative infective complications. Antibiotic prophylaxis is probably not required in clean, elective breast surgery. (C) 2000 Harcourt Publishers Ltd.

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收藏

页码：363 / 366

页数：4

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