Comparison of radiographic joint space width and magnetic resonance imaging for prediction of knee replacement: A longitudinal case-control study from the Osteoarthritis Initiative

被引：39

作者：

Eckstein, Felix ^{[1
]}

Boudreau, Robert ^{[2
]}

Wang, Zhijie ^{[3
,4
]}

Hannon, Michael J. ^{[3
,4
]}

Duryea, Jeff ^{[5
]}

Wirth, Wolfgang ^{[1
]}

Cotofana, Sebastian ^{[1
]}

Guermazi, Ali ^{[6
,7
]}

Roemer, Frank ^{[6
,7
,8
]}

Nevitt, Michael ^{[9
]}

John, Markus R. ^{[10
]}

Ladel, Christoph ^{[11
]}

Sharma, Leena ^{[12
]}

Hunter, David J. ^{[13
,14
]}

Kwoh, C. Kent ^{[15
,16
]}

机构：

[1] Paracelsus Med Univ, Salzburg & Nuremberg Austria & Chondrometr GmbH, Inst Anat, Ainring, Germany

[2] Univ Pittsburgh, Grad Sch Publ Hlth, Dept Epidemiol, Pittsburgh, PA USA

[3] Univ Pittsburgh, Div Rheumatol & Clin Immunol, Pittsburgh, PA USA

[4] Pittsburgh VAHS, Pittsburgh, PA USA

[5] Harvard Univ, Brigham & Womens Hosp, Sch Med, Boston, MA 02115 USA

[6] Boston Univ, Boston, MA 02215 USA

[7] Boston Imaging Core Lab BICL LLC, Boston, MA USA

[8] Univ Erlangen Nurnberg, Dept Radiol, D-91054 Erlangen, Germany

[9] UCSF, OAI Coordinating Ctr, San Francisco, CA USA

[10] Novartis Pharma AG, Basel, Switzerland

[11] Merck KGaA, Darmstadt, Germany

[12] Northwestern Univ, Dept Med, Feinberg Sch Med, Chicago, IL 60611 USA

[13] Univ Sydney, Royal N Shore Hosp, Sydney, NSW 2006, Australia

[14] Univ Sydney, Kolling Inst, Inst Bone & Joint Res, Sydney, NSW 2006, Australia

[15] Univ Arizona, Div Rheumatol, Tucson, AZ USA

[16] Univ Arizona, Arthrit Ctr, Tucson, AZ USA

来源：

EUROPEAN RADIOLOGY | 2016年 / 26卷 / 06期

基金：

美国国家卫生研究院;

关键词：

Magnetic resonance imaging; Radiographic joint space width (JSW); Knee osteoarthritis; Clinical validation; Measurement performance; CARTILAGE LOSS; FOLLOW-UP; MRI; SURGERY; RISK;

D O I：

10.1007/s00330-015-3977-8

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

100231 [临床病理学]; 100902 [航空航天医学];

摘要：

To evaluate whether change in fixed-location measures of radiographic joint space width (JSW) and cartilage thickness by MRI predict knee replacement. Knees replaced between 36 and 60 months' follow-up in the Osteoarthritis Initiative were each matched with one control by age, sex and radiographic status. Radiographic JSW was determined from fixed flexion radiographs and subregional femorotibial cartilage thickness from 3 T MRI. Changes between the annual visit before replacement (T-0) and 2 years before T-0 (T-2) were compared using conditional logistic regression. One hundred and nineteen knees from 102 participants (55.5 % women; age 64.2 +/- 8.7 [mean +/- SD] years) were studied. Fixed-location JSW change at 22.5 % from medial to lateral differed more between replaced and control knees (case-control [cc] OR = 1.57; 95 % CI: 1.23-2.01) than minimum medial JSW change (ccOR = 1.38; 95 % CI: 1.11-1.71). Medial femorotibial cartilage loss displayed discrimination similar to minimum JSW, and central tibial cartilage loss similar to fixed-location JSW. Location-independent thinning and thickening scores were elevated prior to knee replacement. Discrimination of structural progression between knee pre-placement cases versus controls was stronger for fixed-location than minimum radiographic JSW. MRI displayed similar discrimination to radiography and suggested greater simultaneous cartilage thickening and loss prior to knee replacement. aEuro cent Fixed-location JSW predicts surgical knee replacement more strongly than minimum JSW. aEuro cent MRI predicts knee replacement with similar accuracy to radiographic JSW. aEuro cent MRI reveals greater cartilage thinning and thickening prior to knee replacement.

引用

页码：1942 / 1951

页数：10

共 28 条

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Total joint replacement after glucosamine sulphate treatment in knee osteoarthritis:: results of a mean 8-year observation of patients from two previous 3-year, randomised, placebo-controlled trials [J].