The arsenical resistance operon of IncN plasmid R46

被引：59

作者：

Bruhn, DF

Li, JX

Silver, S

Roberto, F

Rosen, BP

机构：

[1] UNIV ILLINOIS,DEPT MICROBIOL & IMMUNOL,CHICAGO,IL 60612

[2] IDAHO NATL ENGN LAB,DEPT BIOTECHNOL,IDAHO FALLS,ID 83415

[3] WAYNE STATE UNIV,DEPT BIOCHEM,SCH MED,DETROIT,MI 48201

来源：

FEMS MICROBIOLOGY LETTERS | 1996年 / 139卷 / 2-3期

关键词：

arsenic; antimony; plasmid resistance; anion pump; ATPase; metalloregulation;

D O I：

10.1016/0378-1097(96)00134-6

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The arsenical resistance operon of the IncN plasmid R46 consists of 4696 bp and starts with predicted transcriptional control and initiation signals, followed by five genes, arsR, arsD, arsA, arsB and ausC. The corresponding Escherichia coli chromosomal aus operon and two staphylococcal aus operons lack arsA and arsD genes, The R46 system contains only the second known versions of arsA and arsD, after those of plasmid R773. Western blot analysis identified the R46 proteins using antibodies against R773 ArsA, ArsC, ArsD and ArsR.

引用

页码：149 / 153

页数：5

共 24 条

[1] ARSENIC EFFLUX GOVERNED BY THE ARSENIC RESISTANCE DETERMINANT OF STAPHYLOCOCCUS-AUREUS PLASMID PI258 [J].