Subpopulations at increased risk of adverse health outcomes from air pollution

被引:55
作者
Annesi-Maesano, I [1 ]
Agabiti, N
Pistelli, R
Couilliot, MF
Forastiere, F
机构
[1] INSERM, U742, Dept Epidemiol Immediate Hypersensit, F-94807 Villejuif, France
[2] Epidemiol & Biostat, Villejuif, France
[3] ASL RME, Dept Epidemiol, Rome, Italy
[4] Univ Cattolica Sacro Cuore, Dept Clin Med, Rome, Italy
[5] Sch Med Paris XIII, Dept Publ Hlth, Bobigny, France
关键词
air pollution; elderly; gendcr; respiratory diseases; sex; susceptibility;
D O I
10.1183/09031936.03.00402103
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Epidemiological research to identify subpopulations with enhanced susceptibility to air pollution is still at an early stage. From the available studies, there is evidence that both "endogenous" and "exogenous" factors contribute to individual susceptibility. Females and the elderly are at an increased risk of pollution-related diseases. Moreover, some chronic clinical conditions seem to be good candidates for identifying the "frail" populations: chronic obstructive pulmonary disease including asthma, coronary heart diseases, congestive heart failure, and heart rhythm disorders. It seems clear that epidemiological research on susceptibility in the future should investigate the underlying biological and physiological mechanisms, in addition to the environmental and toxicological effects.
引用
收藏
页码:57S / 63S
页数:7
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