New and efficient synthetic routes to 1-deoxy-D-xylulose

被引：38

作者：

Giner, JL ^{[1
]}

机构：

[1] Syracuse Univ, Dept Chem, ESF, Syracuse, NY 13210 USA

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 17期

关键词：

D O I：

10.1016/S0040-4039(98)00310-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The biochemically important deoxysugar 1-deoxy-D-xylulose was synthesized by improved methods. D-Tartaric acid is the starting material for a synthesis which proceeds via the intermediacy of 2,3,4-tribenzyl-D-threitol. Another, highly efficient route used the Sharpless asymmetric dihydroxylation of 5-benzyloxy-3-penten-2-one as its key step. These syntheses are especially useful for isotopic labeling. (C) 1998 Published by Elsevier Science Ltd. All rights reserved.

引用

页码：2479 / 2482

页数：4

共 17 条

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