Synthesis of highly substituted 1,3-butadienes by palladium-catalyzed arylation of internal alkynes

被引：77

作者：

Satoh, T ^{[1
]}

Ogino, S ^{[1
]}

Miura, M ^{[1
]}

Aromitra, M ^{[1
]}

机构：

[1] Osaka Univ, Fac Engn, Dept Appl Chem, Suita, Osaka 5650871, Japan

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2004年 / 43卷 / 38期

关键词：

alkynes; arylation; C-C coupling; homogeneous catalysis; palladium;

D O I：

10.1002/anie.200460409

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Four molecules are coupled together by the single treatment of aryl boronic acids with alkynes in the absence or presence of iodobenzene under palladium catalysis to afford 1,4-diaryl-1,3-butadienes as the major product. Addition of a silver salt as oxidant and/or base effectively enables the selective catalytic production of the π-conjugated compounds.

引用

页码：5063 / 5065

页数：3

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