Diffusion tensor imaging can detect and quantify corticospinal tract degeneration after stroke

被引：315

作者：

Werring, DJ ^{[1
]}

Toosy, AT ^{[1
]}

Clark, CA ^{[1
]}

Parker, GJM ^{[1
]}

Barker, GJ ^{[1
]}

Miller, DH ^{[1
]}

Thompson, AJ ^{[1
]}

机构：

[1] UCL Inst Neurol, NMR Res Unit, London WC1N 3BG, England

来源：

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY | 2000年 / 69卷 / 02期

关键词：

magnetic resonance imaging; diffusion tensor; stroke; pathophysiology;

D O I：

10.1136/jnnp.69.2.269

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Diffusion tensor imaging (DTI) fully characterises water molecule mobility in vivo, allowing an exploration of fibre tract integrity and orientation in the human brain. Using DTI this study demonstrates reduced fibre coherence (anisotropy) associated with cerebral infarction and in the corticospinal tract remote from the lesion, in five patients 2 to 6 months after ischaemic stroke. The study highlights the potential of DTI to detect and monitor the structural degeneration of fibre pathways, which may provide a better understanding of the pattern of clinical evolution after stroke.

引用

页码：269 / 272

页数：4

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