Potential adverse health effects of genetically modified crops

被引:34
作者
Bakshi, A [1 ]
机构
[1] George Mason Univ, Dept Biol, Fairfax, VA 22030 USA
来源
JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS | 2003年 / 6卷 / 03期
关键词
D O I
10.1080/10937400306469
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
Genetically modified crops have the potential to eliminate hunger and starvation in millions of people, especially in developing countries because the genetic modification can produce large amounts of foods that are more nutritious. Large quantities are produced because genetically modified crops are more resistant to pests and drought. They also contain greater amounts of nutrients, such as proteins and vitamins. However, there are concerns about the safety of genetically modified crops. The concerns are that they may contain allergenic substances due to introduction of new genes into crops. Another concern is that genetic engineering often involves the use of antibiotic-resistance genes as "selectable markers" and this could lead to production of antibiotic-resistant bacterial strains that are resistant to available antibiotics. This would create a serious public health problem. The genetically modified crops might contain other toxic substances ( such as enhanced amounts of heavy metals) and the crops might not be "substantially equivalent" in genome, proteome, and metabolome compared with unmodified crops. Another concern is that genetically modified crops may be less nutritious; for example, they might contain lower amounts of phytoestrogens, which protect against heart disease and cancer. The review of available literature indicates that the genetically modified crops available in the market that are intended for human consumption are generally safe; their consumption is not associated with serious health problems. However, because of potential for exposure of a large segment of human population to genetically modified foods, more research is needed to ensure that the genetically modified foods are safe for human consumption.
引用
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页码:211 / 225
页数:15
相关论文
共 66 条
[1]  
Acosta A., 2000, AMERICAS, V52, P14
[2]  
[Anonymous], GEN MOD PEST PROT PL
[3]  
[Anonymous], N ENGL J MED
[4]  
[Anonymous], 402 ROYAL SOC
[5]  
[Anonymous], 1998, GEN MOD PLANTS FOOD
[6]  
ANTONIOU M, 1999, SAFETY GENETICALLY E
[7]   Stability of food allergens to digestion in vitro [J].
Astwood, JD ;
Leach, JN ;
Fuchs, RL .
NATURE BIOTECHNOLOGY, 1996, 14 (10) :1269-1273
[8]   Safety and advantages of Bacillus thuringiensis-protected plants to control insect pests [J].
Betz, FS ;
Hammond, BG ;
Fuchs, RL .
REGULATORY TOXICOLOGY AND PHARMACOLOGY, 2000, 32 (02) :156-173
[9]  
BURDOCK GA, 2002, TOXICOLOGIST, V66, P381
[10]   Bacillus thuringiensis use in agriculture: A molecular perspective [J].
Cannon, RJC .
BIOLOGICAL REVIEWS, 1996, 71 (04) :561-636