Treatment of chronic, nonhealing abdominal wound in a liquid environment

被引：20

作者：

Eriksson, E ^{[1
]}

Perez, N ^{[1
]}

Slama, J ^{[1
]}

Page, CP ^{[1
]}

Andree, C ^{[1
]}

Maguire, JH ^{[1
]}

机构：

[1] BRIGHAM & WOMENS HOSP,DEPT INFECT DIS,BOSTON,MA 02115

来源：

ANNALS OF PLASTIC SURGERY | 1996年 / 36卷 / 01期

关键词：

D O I：

10.1097/00000637-199601000-00016

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

A 66-year-old woman with an abdominal wound caused by infected synthetic mesh had failed to heal in spite of many surgical attempts to close the wound. A sealed transparent vinyl chamber was glued to the periphery of the wound and antibiotics in high concentrations (up to 2,500 times the minimum inhibitory concentration) were delivered through the chamber, The wound fluid in the chamber was used for analysis of microbial activity, concentration of residual antibiotics, and growth factor activity. After 10 weeks of treatment, the wound was closed and has not recurred in 24 months.

引用

页码：80 / 83

页数：4

共 12 条

[1] IN-VIVO TRANSFER AND EXPRESSION OF A HUMAN EPIDERMAL GROWTH-FACTOR GENE ACCELERATES WOUND REPAIR [J].

ANDREE, C ;

SWAIN, WF ;

PAGE, CP ;

MACKLIN, MD ;

SLAMA, J ;

HATZIS, D ;

ERIKSSON, E .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (25) :12188-12192

[2] HEALING OF PARTIAL THICKNESS PORCINE SKIN WOUNDS IN A LIQUID ENVIRONMENT [J].

BREUING, K ;

ERIKSSON, E ;

LIU, P ;

MILLER, DR .

JOURNAL OF SURGICAL RESEARCH, 1992, 52 (01) :50-58

[3]

BUNYAN J, 1940, P ROY SOC MED, V34, P65

[4]

DAYTON MT, 1986, ARCH SURG-CHICAGO, V121, P954

[5]

ERIKSSON E, 1989, Surgical Forum (Chicago), V40, P618

[6]

Hebra F., 1861, ALLGEMEINE WIENER ME, V6, P351

[7]

Hudson R V, 1941, Br Med J, V2, P7

[8]

LAWRENCE WT, 1992, WOUND HEALING BIOCH, P541

[9] APPEARANCE OF HEPARIN-BINDING EGF-LIKE GROWTH-FACTOR IN WOUND FLUID AS A RESPONSE TO INJURY [J].

MARIKOVSKY, M ;

BREUING, K ;

LIU, PY ;

ERIKSSON, E ;

HIGASHIYAMA, S ;

FARBER, P ;

ABRAHAM, J ;

KLAGSBRUN, M .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (09) :3889-3893

[10] GENETICALLY-MODIFIED KERATINOCYTES TRANSPLANTED TO WOUNDS RECONSTITUTE THE EPIDERMIS [J].

VOGT, PM ;

THOMPSON, S ;

ANDREE, C ;

LIU, P ;

BREUING, K ;

HATZIS, D ;

BROWN, H ;

MULLIGAN, RC ;

ERIKSSON, E .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (20) :9307-9311

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