Parity among atopic and non-atopic mothers

被引：27

作者：

Nilssen, L ^{[1
]}

Kjellman, NLM

Lofman, O

Bjorksten, B

机构：

[1] Linkoping Univ, Dept Hlth & Environm, Div Paediat, S-58185 Linkoping, Sweden

[2] Ctr Publ Hlth Sci, Dept Community & Environm Med, Linkoping, Sweden

来源：

PEDIATRIC ALLERGY AND IMMUNOLOGY | 1997年 / 8卷 / 03期

关键词：

hypersensitivity; parity;

D O I：

10.1111/j.1399-3038.1997.tb00166.x

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

A temporary Th2 skewed immunity is essential for a successful outcome of pregnancy. It is also a hallmark of atopic disease. We recorded the number of siblings to 3667 children in relation to maternal atopy. In all, 65 % of the allergic and 56 % of the non allergic mothers had more than one child (p < 0.001). These data support a hypothesis that the atopic genotype may be associated with an increased likelihood for a successful outcome of pregnancy and thus from an evolutionary point of view compensate for the less efficient host defence against microbial infections associated with this type of immunity.

引用

页码：134 / 136

页数：3

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