Dysregulation of P2X7 receptor-inflammasome axis in SAPHO syndrome: successful treatment with anakinra

被引：65

作者：

Colina, Matteo ^{[1
]}

Pizzirani, Cinzia ^{[2
,3
]}

Khodeir, Micheline ^{[4
]}

Falzoni, Simonetta ^{[2
,3
]}

Bruschi, Marco ^{[1
]}

Trotta, Francesco ^{[1
]}

Di Virgilio, Francesco ^{[2
,3
]}

机构：

[1] Univ Ferrara, Rheumatol Sect, Dept Clin & Expt Med, I-44100 Ferrara, Italy

[2] Univ Ferrara, ICSI, I-44100 Ferrara, Italy

[3] Univ Ferrara, Dept Expt & Diagnost Med, Sect Gen Pathol, I-44100 Ferrara, Italy

[4] Univ Ferrara Arcispedale St Anna, Azienda Osped, Microbiol Sect, Dept Radiol & Clin Pathol, Ferrara, Italy

来源：

RHEUMATOLOGY | 2010年 / 49卷 / 07期

关键词：

OSTEITIS SYNDROME; HYPEROSTOSIS; PUSTULOSIS; IL-1-BETA; SYNOVITIS; RELEASE; ACNE; ATP;

D O I：

10.1093/rheumatology/keq074

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：1416 / 1418

页数：4

共 8 条

[1] Clinical and Radiologic Evolution of Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis Syndrome: A Single Center Study of a Cohort of 71 Subjects [J].

Colina, Matteo ;

Govoni, Marcello ;

Orzincolo, Carlo ;

Trotta, Francesco .

ARTHRITIS & RHEUMATISM-ARTHRITIS CARE & RESEARCH, 2009, 61 (06) :813-821

[2] Immunological and Inflammatory Functions of the Interleukin-1 Family [J].

Dinarello, Charles A. .

ANNUAL REVIEW OF IMMUNOLOGY, 2009, 27 :519-550

[3]

Ferrari D, 1997, J IMMUNOL, V159, P1451

[4] The P2X7 receptor:: A key player in IL-1 processing and release [J].

Ferrari, Davide ;

Pizzirani, Cinzia ;

Adinolfi, Elena ;

Lemoli, Roberto M. ;

Curti, Antonio ;

Idzko, Marco ;

Panther, Elisabeth ;

Di Virgilio, Francesco .

JOURNAL OF IMMUNOLOGY, 2006, 176 (07) :3877-3883

[5] Ilium osteitis as the main manifestation of the SAPHO syndrome:: Response to infliximab therapy and review of the literature [J].

Moll, Concepcion ;

Hernandez, M. Victoria ;

Canete, Juan D. ;

Gomez-Puerta, Jose A. ;

Soriano, Alex ;

Collado, Antonio ;

Sarimarti, Raimon .

SEMINARS IN ARTHRITIS AND RHEUMATISM, 2008, 37 (05) :299-306

[6] ATP is released by monocytes stimulated with pathogen-sensing receptor ligands and induces IL-1β and IL-18 secretion in an autocrine way [J].

Piccini, Alessandra ;

Carta, Sonia ;

Tassi, Sara ;

Lasiglie, Denise ;

Fossati, Gianluca ;

Rubartelli, Anna .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2008, 105 (23) :8067-8072

[7] Conundrums in nosology: Synovitis, acne, pustulosis, hyperostosis, and osteitis syndrome and spondylarthritis [J].

Rohekar, G. ;

Inman, R. D. .

ARTHRITIS & RHEUMATISM-ARTHRITIS CARE & RESEARCH, 2006, 55 (04) :665-669

[8] Sustained response to tumor necrosis factor α-blocking agents in two patients with SAPHO syndrome [J].

Wagner, AD ;

Andresen, J ;

Jendro, MC ;

Hülsemann, JL ;

Zeidler, H .

ARTHRITIS AND RHEUMATISM, 2002, 46 (07) :1965-1968

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