The prevalence of abnormal glucose regulation in patients with coronary artery disease across Europe -: The Euro Heart Survey on diabetes and the heart

被引:498
作者
Bartnik, M [1 ]
Rydén, L
Ferrari, R
Malmberg, K
Pyörälä, K
Simoons, M
Standl, E
Soler-Soler, J
Öhrvik, J
机构
[1] Karolinska Univ Hosp, Dept Cardiol, Stockholm, Sweden
[2] Gornoslaskie Ctr Med, Dept Cardiol 3, Silesian Sch Med, Katowice, Poland
[3] Univ Ferrara, Inst Biofis Carlos Chagas Filho, Chair Cardiol, Ferrara, Italy
[4] Fdn S Maugeri, Ferrara, Italy
[5] Kuopio Univ Hosp, Dept Med, Kuopio, Finland
[6] Erasmus Univ, Ctr Med, Ctr Thorax, Dept Cardiol, Rotterdam, Netherlands
[7] Teaching Hosp, Dept Med Endocrinol, Munich, Germany
[8] Hosp Univ Vall Hebron, Serv Cardiol, Barcelona, Spain
[9] Karolinska Inst, Dept Epidemiol & Biostat, Stockholm, Sweden
关键词
coronary artery disease; diabetes mellitus; impaired glucose tolerance; oral glucose tolerance test;
D O I
10.1016/j.ehj.2004.07.027
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Aim The objective behind the Euro Heart Survey on diabetes and the heart was to study the prevalence of abnormal glucose regulation in adult patients with coronary artery disease (CAD). Methods and results The survey engaged 110 centres in 25 countries recruiting 4196 patients referred to a cardiologist due to CAD out of whom 2107 were admitted on an acute basis and 2854 had an elective consultation. Patient data were collected via a web-based case record form. An oral glucose tolerance test (OGTT) was used for the characterisation of the glucose metabolism. Thirty-one per cent of the patients had diabetes. An OGTT was performed on the 1920 patients without known diabetes, of whom 923 had acute and 997 had a stable manifestation of CAD, respectively. In patients with acute CAD, 36% had impaired glucose regulation and 22% newly detected diabetes. In the stable group these proportions were 37% and 14%. Conclusion This survey demonstrates that normal glucose regulation is less common than abnormal glucose regulation in patients with CAD. OGTT easily discloses the glucometabolic state and should be a routine procedure. The knowledge of glucometabolic state among these patients should influence their future management because it has great potential to improve the outcome. (C) 2004 The European Society of Cardiology. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:1880 / 1890
页数:11
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