Some assembly required

被引:17
作者
Kowalczykowski, SC [1 ]
机构
[1] Univ Calif Davis, Microbiol Sect, Davis, CA 95616 USA
[2] Univ Calif Davis, Sect Mol & Cellular Biol, Davis, CA 95616 USA
[3] Univ Calif Davis, Ctr Genet & Dev, Davis, CA 95616 USA
关键词
D O I
10.1038/81923
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Many biological processes require the ordered assembly and disassembly of complex structures. By using common structural elements, conformational switching and competitive interactions, the proper temporal assembly of the structures is assured, while simultaneously taking full advantage of combinatorial flexibility.
引用
收藏
页码:1087 / 1089
页数:3
相关论文
共 20 条
[1]  
Araújo SJ, 2000, MUTAT RES-DNA REPAIR, V459, P171
[2]   Protein complexes in nucleotide excision repair [J].
Araújo, SJ ;
Wood, RD .
MUTATION RESEARCH-DNA REPAIR, 1999, 435 (01) :23-33
[3]   Novel homologs of replication protein A in Archaea: implications for the evolution of ssDNA-binding proteins [J].
Chedin, F ;
Seitz, EM ;
Kowalczykowski, SC .
TRENDS IN BIOCHEMICAL SCIENCES, 1998, 23 (08) :273-277
[4]   Rad52 associates with RPA and functions with Rad55 and Rad57 to assemble meiotic recombination complexes [J].
Gasior, SL ;
Wong, AK ;
Kora, Y ;
Shinohara, A ;
Bishop, DK .
GENES & DEVELOPMENT, 1998, 12 (14) :2208-2221
[5]   Action of DNA repair endonuclease ERCC1/XPF in living cells [J].
Houtsmuller, AB ;
Rademakers, S ;
Nigg, AL ;
Hoogstraten, D ;
Hoeijmakers, JHJ ;
Vermeulen, W .
SCIENCE, 1999, 284 (5416) :958-961
[6]   Identification and characterization of a single-stranded DNA-binding protein from the archaeon Methanococcus jannaschii [J].
Kelly, TJ ;
Simancek, P ;
Brush, GS .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (25) :14634-14639
[7]  
KORNBERG A, 1992, DNA REPLICATION
[8]   Saccharomyces Ku70, Mre11/Rad50, and RPA proteins regulate adaptation to G2/M arrest after DNA damage [J].
Lee, SE ;
Moore, JK ;
Holmes, A ;
Umezu, K ;
Kolodner, RD ;
Haber, JE .
CELL, 1998, 94 (03) :399-409
[9]   Structural basis for the recognition of DNA repair proteins UNG2, XPA, and RAD52 by replication factor RPA [J].
Mer, G ;
Bochkarev, A ;
Gupta, R ;
Bochkareva, E ;
Frappier, L ;
Ingles, CJ ;
Edwards, AM ;
Chazin, WJ .
CELL, 2000, 103 (03) :449-456
[10]   Rad52 protein stimulates DNA strand exchange by Rad51 and replication protein A [J].
New, JH ;
Sugiyama, T ;
Zaitseva, E ;
Kowalczykowski, SC .
NATURE, 1998, 391 (6665) :407-410