Comparison of overall brain volume and midsagittal corpus callosum surface area as obtained from NMR scans and direct anatomical measures:: a within-subject study on autopsy brains

被引：17

作者：

Peters, M ^{[1
]}

Jäncke, L

Zilles, K

机构：

[1] Univ Guelph, Dept Psychol, Guelph, ON N1G 2Z5, Canada

[2] Univ Magdeburg, D-39106 Magdeburg, Germany

[3] Univ Dusseldorf, Res Ctr Julich, Dusseldorf, Germany

来源：

NEUROPSYCHOLOGIA | 2000年 / 38卷 / 10期

基金：

加拿大自然科学与工程研究理事会;

关键词：

brain; size; volume; NMR; corpus callosum;

D O I：

10.1016/S0028-3932(00)00048-8

中图分类号：

B84 [心理学]; C [社会科学总论]; Q98 [人类学];

学科分类号：

03 ; 0303 ; 030303 ; 04 ; 0402 ;

摘要：

Formalin fixed brains obtained from autopsy were studied by magnetic resonance imaging. using FLASH and MPR sequences. The overall volume and the midsagittal surface area of the corpus callosum (cc) of these brains were also directly measured by water displacement for overall volume determination and morphometry for cc surface area measures, allowing comparisons of these measures in a within-subject design. Thin NMR sections (1 mm thickness for FLASH and 1.25 mm for MPR) yielded overall brain volume estimates that did not differ significantly from direct volume estimations but thicker (5 mm) sections led to a significant overestimation of brain volume for NMR measures relative to direct displacement measures. There was no overall effect of type of NMR measure: FLASH and MPR scans did not yield significantly different values for overall brain volume or callosal surface area. Direct and NMR measures of the corpus callosum surface at midsagittal level did not yield significantly different estimates. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：1375 / 1381

页数：7

共 24 条

[1]

ABOITIZ F, 1996, BRAIN BEHAV EVOLUT, V47, P25

[2]

Appel FW, 1942, HUM BIOL, V14, P235

[3] Genetic variability of human brain size and cortical gyral patterns [J].