Mouse biodiversity in the genomic era

被引：204

作者：

Galtier, N ^{[1
]}

Bonhomme, F ^{[1
]}

Moulia, C ^{[1
]}

Belkhir, K ^{[1
]}

Caminade, P ^{[1
]}

Desmarais, E ^{[1
]}

Duquesne, JJ ^{[1
]}

Orth, A ^{[1
]}

Dod, B ^{[1
]}

Boursot, P ^{[1
]}

机构：

[1] Univ Montpellier 2, UMR Genome Populat Interact Adaptat 5171, F-34095 Montpellier, France

来源：

CYTOGENETIC AND GENOME RESEARCH | 2004年 / 105卷 / 2-4期

关键词：

D O I：

10.1159/000078211

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Comparative genomics has developed by comparison of distantly related genomes, for which the link between the reported evolutionary changes and species development/ physiology/ecology is not obvious. It is argued that the mouse ( genus Mus) is an optimal model for microevolutionary genomics in vertebrates. This is because the mouse genome sequence, physical and genetic map have been completed, because mouse genetics, morpho-anatomy, pathology, behavior and ecology are well-studied, and because the Mus genus is a diverse, well-documented taxon, allowing comparative studies at the level of individual, population, subspecies, and species. The potential of the interaction between mouse genome and mouse biodiversity is illustrated by recent studies of speciation in the house mouse Mus musculus, and studies about the evolution of isochores, the peculiar pattern of GC-content variation across mammalian genomes. Copyright (C) 2004 S. Karger AG, Basel.

引用

页码：385 / 394

页数：10

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