Developmental biology - One cell, two fates

被引:57
作者
Carmeliet, P [1 ]
机构
[1] Katholieke Univ Leuven, Ctr Transgene Technol & Gene Therapy, B-3000 Louvain, Belgium
关键词
D O I
10.1038/35040684
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
The two types of cell that make up blood vessels can develop from the same precursor. This discovery might improve our understanding of the role of blood vessels in disorders ranging from cancer to heart disease.
引用
收藏
页码:43 / 45
页数:2
相关论文
共 15 条
[1]   Haemopoietic origin of myofibroblasts formed in the peritoneal cavity in response to a foreign body [J].
Campbell, JH ;
Efendy, JL ;
Han, CL ;
Girjes, AA ;
Campbell, GR .
JOURNAL OF VASCULAR RESEARCH, 2000, 37 (05) :364-371
[2]   Mechanisms of angiogenesis and arteriogenesis [J].
Carmeliet, P .
NATURE MEDICINE, 2000, 6 (04) :389-395
[3]   Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele [J].
Carmeliet, P ;
Ferreira, V ;
Breier, G ;
Pollefeyt, S ;
Kieckens, L ;
Gertsenstein, M ;
Fahrig, M ;
Vandenhoeck, A ;
Harpal, K ;
Eberhardt, C ;
Declercq, C ;
Pawling, J ;
Moons, L ;
Collen, D ;
Risau, W ;
Nagy, A .
NATURE, 1996, 380 (6573) :435-439
[4]   Angiogenesis in cancer and other diseases [J].
Carmeliet, P ;
Jain, RK .
NATURE, 2000, 407 (6801) :249-257
[5]   MOLECULAR REGULATION OF ATRIOVENTRICULAR VALVULOSEPTAL MORPHOGENESIS [J].
EISENBERG, LM ;
MARKWALD, RR .
CIRCULATION RESEARCH, 1995, 77 (01) :1-6
[6]  
Gittenberger-de Groot AC, 1999, ARTERIOSCL THROM VAS, V19, P1589
[7]  
Hellström M, 1999, DEVELOPMENT, V126, P3047
[8]   PDGF, TGF-β, and heterotypic cell-cell interactions mediate endothelial cell-induced recruitment of 10T1/2 cells and their differentiation to a smooth muscle fate [J].
Hirschi, KK ;
Rohovsky, SA ;
D'Amore, PA .
JOURNAL OF CELL BIOLOGY, 1998, 141 (03) :805-814
[9]   Angiogenesis and vasculogenesis as therapeutic strategies for postnatal neovascularization [J].
Isner, JM ;
Asahara, T .
JOURNAL OF CLINICAL INVESTIGATION, 1999, 103 (09) :1231-1236
[10]   Endothelial-perivascular cell signaling in vascular development:: lessons from knockout mice [J].
Lindahl, P ;
Hellström, M ;
Kalén, M ;
Betsholtz, C .
CURRENT OPINION IN LIPIDOLOGY, 1998, 9 (05) :407-411