Mixtures of chiral and achiral monodentate ligands in asymmetric Rh-catalyzed olefin hydrogenation: reversal of enantioselectivity

被引：127

作者：

Reetz, MT ^{[1
]}

Mehler, G ^{[1
]}

机构：

[1] Max Planck Inst Kohlenforsch, D-45470 Mulheim, Germany

来源：

TETRAHEDRON LETTERS | 2003年 / 44卷 / 24期

关键词：

asymmetric catalysis; combinatorial chemistry; phosphorus ligands; hydrogenation; rhodium;

D O I：

10.1016/S0040-4039(03)00976-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The recently described method of combinatorial asymmetric transition metal catalysis based oil the use of mixtures of chiral monodentate P-ligands has been extended to include mixtures of chiral and a chiral monodentate P-ligands, reversal of enantioselectivity in Rh-catalyzed olefin hydrogenation being possible in appropriate cases. (C) 2003 Elsevier Science Ltd. All rights reserved.

引用

页码：4593 / 4596

页数：4

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