Increased skin lactate in complex regional pain syndrome:: Evidence for tissue hypoxia?

被引：66

作者：

Birklein, F ^{[1
]}

Weber, M ^{[1
]}

Neundörfer, B ^{[1
]}

机构：

[1] Univ Erlangen Nurnberg, Inst Physiol 1, Neurol Klin, D-91054 Erlangen, Germany

来源：

NEUROLOGY | 2000年 / 55卷 / 08期

关键词：

D O I：

10.1212/WNL.55.8.1213

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

To investigate oxygen metabolism in complex regional pain syndrome (CRPS), the authors measured skin lactate via dermal microdialysis performed on patients with CRPS (n = 11) and healthy control subjects (n = 11). In addition, they measured blood lactate. Although venous lactate was unaltered, skin lactate was increased in patients with CRPS (2.95 mmol/L; control subjects 1.74 mmol/L; p < 0.005). These results suggest enhanced anaerobic glycolysis, probably as a result of chronic tissue hypoxia.

引用

页码：1213 / 1215

页数：3

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