Comparison of biochemical blood traits after long-term selection on high or low locomotory activity in mice

被引：16

作者：

Falkenberg, H ^{[1
]}

Langhammer, M ^{[1
]}

Renne, U ^{[1
]}

机构：

[1] Inst Appl Agroecol Rostock, D-18059 Rostock, Germany

来源：

ARCHIV FUR TIERZUCHT-ARCHIVES OF ANIMAL BREEDING | 2000年 / 43卷 / 05期

关键词：

mouse; long-term selection; treadmill performance; selection response; blood traits; substrates; enzymes;

D O I：

10.5194/aab-43-513-2000

中图分类号：

S8 [畜牧、动物医学、狩猎、蚕、蜂];

学科分类号：

0905 ;

摘要：

In a long term experiment laboratory mice were selected for high (line DU-hTP) or low (line DU-lTP) paternal treadmill performance to differentiate the endurance fitness. In generation 54 six enzymes and seven substrates were investigated in the blood plasma of males and females in DU-hTP (n = 104) and DU-lTP (n = 141). Compared with line DU-lTP in line DU-hTP significantly higher enzyme activities, increased glucose concentration and lower level of triglycerides were found. The components of total cholesterol were divergent between the two lines and positively effected in DU-hTP for higher HDL-cholesterol. Animals with high endurance fitness showed a higher gain in the HDL-cholesterol concentration with increased total cholesterol level in the blood than gain of LDL+VLDL-cholesterol concentration.

引用

页码：513 / 522

页数：10

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