G-protein signaling: Fine-tuning signaling kinetics

被引：69

作者：

Zerangue, N ^{[1
]}

Jan, LY

机构：

[1] Univ Calif San Francisco, Howard Hughes Med Inst, Dept Physiol, Program Neurosci, San Francisco, CA 94143 USA

[2] Univ Calif San Francisco, Howard Hughes Med Inst, Dept Biochem, Program Neurosci, San Francisco, CA 94143 USA

来源：

CURRENT BIOLOGY | 1998年 / 8卷 / 09期

关键词：

D O I：

10.1016/S0960-9822(98)70196-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Mammalian 'regulators of G protein signaling' (RGS proteins) help shut off G-protein-mediated signaling by GTPase activation, But new evidence shows that RGS proteins can also speed up the activation of signaling. The combined effect is a change in signaling kinetics without a decrease in signaling intensity. (C) Current Biology Ltd ISSN 0960-9822.

引用

页码：R313 / R316

页数：4

共 28 条

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