Synthesis of new vanadyl complexes of hydroxyazine-type heterocycles and their insulin-mimetic activities

被引：20

作者：

Katoh, A ^{[1
]}

Taguchi, K

Okada, H

Harata, M

Fujisawa, Y

Takino, T

Sakurai, H

机构：

[1] Seikei Univ, Fac Engn, Dept Ind Chem, Musashino, Tokyo 1808633, Japan

[2] Kyoto Pharmaceut Univ, Dept Analyt & Bioinorgan Chem, Yamashima Ku, Kyoto 6078413, Japan

来源：

CHEMISTRY LETTERS | 2000年 / 08期

关键词：

D O I：

10.1246/cl.2000.866

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Four kinds of vanadyl complexes of hydroxyazine-type heterocycles were synthesized. Bis(1,2-dihydro-4,6-dimethyl-2-oxo-1-pyrimidinolato)- and bis(1,2-dihydro-2-oxo-3,5,6-trimethyl-1-pyrazinolato)oxovanadium(IV) complexes showed higher insulin-mimetic activity than vanadyl sulfate as a positive control.

引用

页码：866 / 867

页数：2

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