Febrile seizures: genetics and relationship to other epilepsy syndromes

被引:42
作者
Berkovic, SF
Scheffer, IE
机构
[1] Univ Melbourne, Dept Med Neurol, Comprehens Epilepsy Program, Austin & Repatriat Med Ctr, Melbourne, Vic 3084, Australia
[2] Royal Childrens Hosp, Dept Neurol, Melbourne, Vic, Australia
关键词
D O I
10.1097/00019052-199804000-00009
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The relationship between febrile seizures and epilepsy has long been debated. We argue that there is some specificity to the types of epilepsy that follow febrile seizures, rather than febrile seizures being a nonspecific marker of a lowered seizure threshold. The relationship between febrile seizures and later epilepsy is frequently genetic. Recent clinical and molecular genetic studies suggest that there are a number of syndrome-specific genes for febrile seizures. (C) 1998 Rapid Science Ltd.
引用
收藏
页码:129 / 134
页数:6
相关论文
共 53 条
[1]   FACTORS PROGNOSTIC OF UNPROVOKED SEIZURES AFTER FEBRILE CONVULSIONS [J].
ANNEGERS, JF ;
HAUSER, WA ;
SHIRTS, SB ;
KURLAND, LT .
NEW ENGLAND JOURNAL OF MEDICINE, 1987, 316 (09) :493-498
[2]  
[Anonymous], 1980, Pediatrics, V66, P1009
[3]   PROPOSAL FOR REVISED CLASSIFICATION OF EPILEPSIES AND EPILEPTIC SYNDROMES [J].
不详 .
EPILEPSIA, 1989, 30 (04) :389-399
[4]  
Baumann RJ, 1996, PEDIATRICS, V97, P773
[5]   RISK-FACTORS FOR A FIRST FEBRILE SEIZURE - A MATCHED CASE-CONTROL STUDY [J].
BERG, AT ;
SHINNAR, S ;
SHAPIRO, ED ;
SALOMON, ME ;
CRAIN, EF ;
HAUSER, WA .
EPILEPSIA, 1995, 36 (04) :334-341
[6]   Unprovoked seizures in children with febrile seizures: Short-term outcome [J].
Berg, AT ;
Shinnar, S .
NEUROLOGY, 1996, 47 (02) :562-568
[7]  
Bergman DA, 1996, PEDIATRICS, V97, P769
[8]   Familial temporal lobe epilepsy: A common disorder identified in twins [J].
Berkovic, SF ;
McIntosh, A ;
Howell, RA ;
Mitchell, A ;
Sheffield, LJ ;
Hopper, JL .
ANNALS OF NEUROLOGY, 1996, 40 (02) :227-235
[9]  
BERKOVIC SF, 1998, IN PRESS ANN NEUROL
[10]   WHICH CHILD WILL HAVE A FEBRILE SEIZURE [J].
BETHUNE, P ;
GORDON, K ;
DOOLEY, J ;
CAMFIELD, C ;
CAMFIELD, P .
AMERICAN JOURNAL OF DISEASES OF CHILDREN, 1993, 147 (01) :35-39