Pathophysiology of upper airway obstruction during sleep

被引：38

作者：

Badr, MS

机构：

[1] Detroit VA Med Ctr, Pulm Sect 111A, Detroit, MI 48201 USA

[2] Wayne State Univ, Sch Med, Dept Med, Detroit, MI 48201 USA

来源：

CLINICS IN CHEST MEDICINE | 1998年 / 19卷 / 01期

关键词：

D O I：

10.1016/S0272-5231(05)70429-9

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

Obstructive sleep apnea is a common medical disorder with significant adverse health consequences. The pathogenesis of pharyngeal obstruction during sleep, however, remains elusive. This article addresses the key mechanisms of upper airway (UA) obstruction including the role of transmural pressure, pharyngeal compliance, pharyngeal dilating muscle activity and non-neuromuscular factors. A proposed scheme of the pathophysiology of UA obstruction is outlined.

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页码：21 / +

页数：13

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