Oligonucleotide adjuvants for T helper 1 (Th1)-specific vaccination

被引：96

作者：

Carson, DA ^{[1
]}

Raz, E ^{[1
]}

机构：

[1] UNIV CALIF SAN DIEGO,DEPT MED,LA JOLLA,CA 92093

来源：

JOURNAL OF EXPERIMENTAL MEDICINE | 1997年 / 186卷 / 10期

关键词：

D O I：

10.1084/jem.186.10.1621

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

引用

页码：1621 / 1622

页数：2

共 18 条

[1] CpG oligodeoxynucleotides act as adjuvants that switch on T helper 1 (Th1) immunity [J].

Chu, RS ;

Targoni, OS ;

Krieg, AM ;

Lehmann, PV ;

Harding, CV .

JOURNAL OF EXPERIMENTAL MEDICINE, 1997, 186 (10) :1623-1631

[2]

Klinman DM, 1997, J IMMUNOL, V158, P3635

[3] CpG motifs present in bacterial DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma [J].

Klinman, DM ;

Yi, AK ;

Beaucage, SL ;

Conover, J ;

Krieg, AM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (07) :2879-2883

[4]

Kreig A. M., 1995, NATURE, V374, P546

[5] INDUCERS OF INTERFERON AND HOST RESISTANCE .I. DOUBLE-STRANDED RNA FROM EXTRACTS OF PENICILLIUM FUNICULOSUM [J].

LAMPSON, GP ;

TYTELL, AA ;

FIELD, AK ;

NEMES, MM ;

HILLEMAN, MR .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1967, 58 (02) :782-&

[6] Activation of human B cells by phosphorothioate oligodeoxynucleotides [J].

Liang, H ;

Nishioka, Y ;

Reich, CF ;

Pisetsky, DS ;

Lipsky, PE .

JOURNAL OF CLINICAL INVESTIGATION, 1996, 98 (05) :1119-1129

[7] Cytokine gene therapy of cancer using interleukin-12: Murine and clinical trials [J].

Lotze, MT ;

Zitvogel, L ;

Campbell, R ;

Robbins, PD ;

Elder, E ;

Haluszczak, C ;

Martin, D ;

Whiteside, TL ;

Storkus, WJ ;

Tahara, H .

INERLEUKIN 12: CELLULAR AND MOLECULAR IMMUNOLOGY OF AN IMPORTANT REGULATORY CYTOKINE, 1996, 795 :440-454

[8]

MESSINA JP, 1991, J IMMUNOL, V147, P1759

[9] Preferential induction of a Th-1 immune response and inhibition of specific IgE antibody formation by plasmid DNA immunization [J].

Raz, E ;

Tighe, H ;

Sato, Y ;

Corr, M ;

Dudler, JA ;

Roman, M ;

Swain, SL ;

Spiegelberg, HL ;

Carson, DA .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (10) :5141-5145

[10] INTRADERMAL GENE IMMUNIZATION - THE POSSIBLE ROLE OF DNA UPTAKE IN THE INDUCTION OF CELLULAR-IMMUNITY TO VIRUSES [J].

RAZ, E ;

CARSON, DA ;

PARKER, SE ;

PARR, TB ;

ABAI, AM ;

AICHINGER, G ;

GROMKOWSKI, SH ;

SINGH, M ;

LEW, D ;

YANKAUCKAS, MA ;

BAIRD, SM ;

RHODES, GH .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (20) :9519-9523

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