Three-component coupling based on the "cation pool" method

被引：90

作者：

Suga, S ^{[1
]}

Nishida, T ^{[1
]}

Yamada, D ^{[1
]}

Nagaki, A ^{[1
]}

Yoshida, J ^{[1
]}

机构：

[1] Kyoto Univ, Grad Sch Engn, Dept Synthet Chem & Biol Chem, Nishikyo Ku, Kyoto 6158510, Japan

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2004年 / 126卷 / 44期

关键词：

D O I：

10.1021/ja0455704

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Sequential one-pot three-component coupling reactions have been developed based on the "cation pool" method. An N-acyliminium ion generated by the "cation pool" method adds to an electron-rich carbon-carbon double bond, such as enamine derivatives and vinyl sulfides, to form the second "cation pool". The addition of nucleophiles such as allylsilanes, enol silyl ethers, Grignard reagents, and organoaluminum compounds led to the formation of the corresponding three-component coupling products. Copyright © 2004 American Chemical Society.

引用

页码：14338 / 14339

页数：2

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