Positive atrial inotropic effect of dofetilide after cardioversion of atrial fibrillation or flutter

被引：12

作者：

DeCara, JM ^{[1
]}

Pollak, A ^{[1
]}

Dubrey, S ^{[1
]}

Falk, RH ^{[1
]}

机构：

[1] Boston Med Ctr, Boston, MA 02118 USA

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 2000年 / 86卷 / 06期

关键词：

D O I：

10.1016/S0002-9149(00)01044-4

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The pure class III agent dofetilide was evaluated to determine its effect on atrial function after cardioversion of atrial fibrillation or flutter. Compared with placebo, dofetilide-treated patients had evidence of better atrial function after cardioversion, indicating that this agent has a positive atrial inotropic effect during the period of postcardioversion atrial stunning.

引用

收藏

页码：685 / +

页数：5

相关论文

共 19 条

[1] EFFECTS OF NEW AND POTENT METHANESULFONANILIDE CLASS-III ANTIARRHYTHMIC AGENTS ON MYOCARDIAL REFRACTORINESS AND CONTRACTILITY IN ISOLATED CARDIAC-MUSCLE [J].

BASKIN, EP ;

SERIK, CM ;

WALLACE, AA ;

BROOKES, LM ;

SELNICK, HG ;

CLAREMON, DA ;

LYNCH, JJ .

JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 1991, 18 (03) :406-414

[2] DETERMINANTS OF DOPPLER INDEXES OF LEFT-VENTRICULAR DIASTOLIC FUNCTION IN NORMAL SUBJECTS (THE FRAMINGHAM HEART-STUDY) [J].

BENJAMIN, EJ ;

LEVY, D ;

ANDERSON, KM ;

WOLF, PA ;

PLEHN, JF ;

EVANS, JC ;

COMAI, K ;

FULLER, DL ;

SUTTON, MS .

AMERICAN JOURNAL OF CARDIOLOGY, 1992, 70 (04) :508-515

[3] Optimal number of beats for the Doppler measurement of cardiac output in atrial fibrillation [J].

Dubrey, SW ;

Falk, RH .

JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY, 1997, 10 (01) :67-71

[4]

Falk RH, 1998, J AM COLL CARDIOL, V31, P1446

[5] Left atrial appendage ''stunning'' after electrical cardioversion of atrial flutter: An attenuated response compared with atrial fibrillation as the mechanism for lower susceptibility to thromboembolic events [J].

Grimm, RA ;

Stewart, WJ ;

Arheart, KL ;

Thomas, JD ;

Klein, AL .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1997, 29 (03) :582-589

[6]

GWILT M, 1991, J PHARMACOL EXP THER, V256, P318

[7] Clinical variables affecting recovery of left atrial mechanical function after cardioversion from atrial fibrillation [J].

Harjai, KJ ;

Mobarek, SK ;

Cheirif, J ;

Boulos, LM ;

Murgo, JP ;

AbiSamra, F .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1997, 30 (02) :481-486

[8] EFFECT OF HEART-RATE ON LEFT-VENTRICULAR DIASTOLIC TRANSMITRAL FLOW VELOCITY PATTERNS ASSESSED BY DOPPLER ECHOCARDIOGRAPHY IN NORMAL SUBJECTS [J].

HARRISON, MR ;

CLIFTON, GD ;

PENNELL, AT ;

DEMARIA, AN ;

CATER, A .

AMERICAN JOURNAL OF CARDIOLOGY, 1991, 67 (07) :622-627

[9] EFFECTS OF THE NEW CLASS-III ANTIARRHYTHMIC DRUG D-SOTALOL ON CONTRACTILE FUNCTION OF POSTISCHEMIC MYOCARDIUM [J].

HOFFMEISTER, HM ;

MULLER, S ;

SEIPEL, L .

JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 1991, 17 (04) :581-586

[10] Hemodynamic effects of antiarrhythmic compounds: Intrinsic effects and autonomic modulation [J].

Hoffmeister, HM ;

Beyer, ME ;

Seipel, L .

AMERICAN JOURNAL OF CARDIOLOGY, 1997, 80 :G24-G30