Nonequilibrium response spectroscopy and the molecular kinetics of proteins

被引：23

作者：

Millonas, MM

Hanck, DA

机构：

[1] Univ Chicago, Dept Pharmacol & Physiol Sci, Chicago, IL 60637 USA

[2] Univ Chicago, Dept Med, Chicago, IL 60637 USA

来源：

PHYSICAL REVIEW LETTERS | 1998年 / 80卷 / 02期

关键词：

D O I：

10.1103/PhysRevLett.80.401

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

Nonequilibrium response spectroscopy is a novel method of analyzing the molecular kinetics of voltage-sensitive proteins that involves measuring of the nonequilibrium response of the molecules to fluctuating fields with large amplitudes and frequencies. This response is exquisitely sensitive to features of the kinetics that are difficult or impossible to resolve by means of more traditional relaxation transient experiments.

引用

页码：401 / 404

页数：4

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