Delayed maturation of the interstitial cells of Cajal: A new diagnosis for transient neonatal pseudoobstruction. Report of two cases

被引:100
作者
Kenny, SE
Vanderwinden, JM
Rintala, RJ
Connell, MG
Lloyd, DA
Vanderhaegen, JJ
De Laet, MH
机构
[1] Free Univ Brussels, Hop Univ Enfants Reine Fabiola, Dept Pediat Surg, Fac Med,Lab Neuropathol, Brussels, Belgium
[2] Univ Liverpool, Liverpool L69 3BX, Merseyside, England
[3] Alder Hey Childrens Hosp, Dept Paediat Surg, Liverpool L12 2AP, Merseyside, England
[4] Alder Hey Childrens Hosp, Inst Child Hlth, Liverpool L12 2AP, Merseyside, England
关键词
neonate; interstitial cells of Cajal; intestinal pseudoobstruction; immunohistochemistry;
D O I
10.1016/S0022-3468(98)90370-0
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
The case histories of two neonates presenting with intestinal pseudoobstruction are presented. One boy infant was premature and the girl infant was full term. Both patients needed a defunctioning ileostomy, and biopsy findings of the intestine in both patients showed a lack of interstitial cells of Cajal (ICC). At the time of closure of the ileostomies to restore intestinal continuity, repeat biopsy results showed a normal pattern of distribution of ICC, Delay in the development of ICC in the gastrointestinal tract may be a cause of intestinal pseudoobstruction in the newborn, Copyright (C) 1998 by W.B. Saunders Company.
引用
收藏
页码:94 / 98
页数:5
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