SmI2-mediated sequential radical cyclization/anionic capture of aryl iodides on solid support

被引:48
作者
Du, XH [1 ]
Armstrong, RW [1 ]
机构
[1] Univ Calif Los Angeles, Dept Chem & Biochem, Los Angeles, CA 90095 USA
基金
美国国家卫生研究院;
关键词
D O I
10.1016/S0040-4039(98)00292-5
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Aryl radicals were generated by SmI2 on solid support, cyclized on to C=C bond, and reduced to their organosamarium anionic species followed by electrophilic capture. However, the capture reaction was substrate-dependant in solution and on solid support. In some examples, results from solid phase reactions were equal or better to the corresponding solution reactions. (C) 1998 Elsevier Science Ltd. All rights reserved.
引用
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页码:2281 / 2284
页数:4
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