A risk-benefit analysis of vaccination

被引:9
作者
Heininger, Ulrich [1 ]
机构
[1] Univ Childrens Hosp Basel, Div Pediat Infect Dis, CH-4005 Basel, Switzerland
关键词
Vaccination; Risk-benefit; CONJUGATE VACCINE; EFFICACY TRIAL; IMMUNIZATION; RUBELLA; CHILDHOOD; PERTUSSIS; CHILDREN; INFANTS; MEASLES; EVENTS;
D O I
10.1016/j.vaccine.2009.10.010
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Impressive success has been achieved worldwide with population based immunisation programmes against several serious infectious diseases. This success is being threatened: the incidence of previously frequent, potentially devastating diseases decreases as a consequence of successful immunisation programmes and attention of the public shifts towards true and alleged "side effects" of vaccines, This can lead to the dilemma of waning public confidence in the necessity, tolerability and safety of vaccinations. Therefore, continuous evaluation of risks and benefits of vaccines is required and results of these need to be communicated broadly to strengthen the confidence in immunisation programmes. (C) 2009 Elsevier Ltd. All rights reserved.
引用
收藏
页码:G9 / G12
页数:4
相关论文
共 22 条
  • [1] THE CONCEPT OF HERD-IMMUNITY AND THE DESIGN OF COMMUNITY-BASED IMMUNIZATION PROGRAMS
    ANDERSON, RM
    [J]. VACCINE, 1992, 10 (13) : 928 - 935
  • [2] Intussusception and rotavirus vaccines
    Bines, Julie
    [J]. VACCINE, 2006, 24 (18) : 3772 - 3776
  • [3] Efficacy, safety and immunogenicity of heptavalent pneumococcal conjugate vaccine in children
    Black, S
    Shinefield, H
    Fireman, B
    Lewis, E
    Ray, P
    Hansen, JR
    Elvin, L
    Ensor, KM
    Hackell, J
    Siber, G
    Malinoski, F
    Madore, D
    Chang, I
    Kohberger, R
    Watson, W
    Austrian, R
    Edwards, K
    [J]. PEDIATRIC INFECTIOUS DISEASE JOURNAL, 2000, 19 (03) : 187 - 195
  • [4] Lack of association between receipt of conjugate Haemophilus influenzae type b vaccine (HbOC) in infancy and risk of type 1 (juvenile onset) diabetes:: Long term follow-up of the HbOC efficacy trial cohort
    Black, SB
    Lewis, E
    Shinefield, HR
    Fireman, B
    Ray, P
    DeStefano, F
    Chen, R
    [J]. PEDIATRIC INFECTIOUS DISEASE JOURNAL, 2002, 21 (06) : 568 - 569
  • [5] The Brighton Collaboration: addressing the need for standardized case definitions of adverse events following immunization (AEFI)
    Bonhoeffer, J
    Kohl, K
    Chen, R
    Duclos, P
    Heijbel, H
    Heininger, U
    Jefferson, T
    Loupi, E
    [J]. VACCINE, 2002, 21 (3-4) : 298 - 302
  • [6] Hypotonic-hyporesponsive episode (HHE) as an adverse event following immunization in early childhood: Case definition and guidelines for data collection, analysis, and presentation
    Buettcher, Michael
    Heininger, Ulrich
    Braun, Miles
    Bonhoeffer, Jan
    Halperin, Scott
    Heijbel, Harald
    Martins, Reinaldo de Menezes
    Vermeer-de Bondt, Patricia
    [J]. VACCINE, 2007, 25 (31) : 5875 - 5881
  • [7] *CDC, 2005, MMWR-MORBID MORTAL W, V57, P144
  • [8] *CDC, 2005, MMWR-MORBID MORTAL W, V54, P893
  • [9] Effectiveness of a mass immunization campaign using serogroup C meningococcal conjugate vaccine
    De Wals, P
    Deceuninck, G
    Boulianne, N
    De Serres, G
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2004, 292 (20): : 2491 - 2494
  • [10] Age at first measles-mumps-rubella vaccination in children with autism and school-matched control subjects: A population-based study in metropolitan Atlanta
    DeStefano, F
    Bhasin, TK
    Thompson, WW
    Yeargin-Allsopp, M
    Boyle, C
    [J]. PEDIATRICS, 2004, 113 (02) : 259 - 266