Interactions between Listeria monocytogenes and host mammalian cells

被引:37
作者
Braun, L [1 ]
Cossart, P [1 ]
机构
[1] Inst Pasteur, Unite Interact Bacteries Cellules, F-75724 Paris 15, France
关键词
Listeria monocytogenes; invasion; signal transduction;
D O I
10.1016/S1286-4579(00)90365-4
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Bacterial pathogens have developed a variety of strategies to induce their own internalization into mammalian cells which are normally nonphagocytic. The Gram-positive bacterium Listeria monocytogenes enters into many cultured cell types using two bacterial surface proteins, InlA (internalin) and InlB. In both cases, entry cakes place after engagement of a receptor and induction of a series of signaling events. (C) 2000 Editions scientifiques et medicales Elsevier SAS.
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页码:803 / 811
页数:9
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