Listeria monocytogenes;
invasion;
signal transduction;
D O I:
10.1016/S1286-4579(00)90365-4
中图分类号:
R392 [医学免疫学];
Q939.91 [免疫学];
学科分类号:
100102 ;
摘要:
Bacterial pathogens have developed a variety of strategies to induce their own internalization into mammalian cells which are normally nonphagocytic. The Gram-positive bacterium Listeria monocytogenes enters into many cultured cell types using two bacterial surface proteins, InlA (internalin) and InlB. In both cases, entry cakes place after engagement of a receptor and induction of a series of signaling events. (C) 2000 Editions scientifiques et medicales Elsevier SAS.