Serotonin and motor activity

被引:242
作者
Jacobs, BL [1 ]
Fornal, CA [1 ]
机构
[1] Princeton Univ, Program Neurosci, Princeton, NJ 08544 USA
关键词
D O I
10.1016/S0959-4388(97)80141-9
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The activity of brain serotonergic neurons in both the pontine-mesencephalic and medullary groups is positively correlated with the level of behavioral arousal and/or the behavioral state. This, in turn, appears to be related to the level of tonic motor activity, especially as manifested in antigravity muscles and other muscle groups associated with gross motor activity. In addition, a subset of serotonergic neurons displays a further increase in activity in association with repetitive, central pattern generator mediated responses. Accumulating evidence indicates that this relation to motor activity is related both to the cc-activation of the sympathetic nervous system and to the modulation of afferent inputs.
引用
收藏
页码:820 / 825
页数:6
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