Accuracy and reproducibility of CFD predicted wall shear stress using 3D ultrasound images

被引:40
作者
Augst, AD
Barratt, DC
Hughes, AD
Glor, FP
Thom, SAM
Xu, XY
机构
[1] Univ London Imperial Coll Sci Technol & Med, Dept Chem Engn & Chem Technol, London SN7 2AZ, England
[2] St Marys Hosp, Dept Clin Pharmacol & Therapeut, London W2 1NY, England
来源
JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME | 2003年 / 125卷 / 02期
关键词
CAROTID-ARTERY BIFURCATIONS; HEMODYNAMICS; FLOW; ATHEROSCLEROSIS; RECONSTRUCTION; ANGIOGRAPHY;
D O I
10.1115/1.1553973
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
Computational fluid dynamics (CFD) flow simulation techniques have the potential to enhance our understanding of how haemodynamic factors are involved in atherosclerosis. Recently, 3D ultrasound has emerged as an alternative to other 3D imaging techniques, such as magnetic resonance angiography (MRA). The method can be used to generate realistic vascular geometry suitable for CFD simulations. In order to assess accuracy and reproducibility of the procedure from image acquisition to reconstruction to CFD simulation, a human carotid artery bifurcation phantom was scanned three times using 3D ultrasound. The geometry was reconstructed and flow simulations were carried out on the three sets as well as on a model generated using computer aided design (CAD) from the geometric information given by the manufacturer It was found that the three reconstructed sets showed good reproducibility as well as satisfactory quantitative agreement with the CAD model. Analyzing two selected locations probably representing the 'worst cases,' accuracy comparing ultrasound and CAD reconstructed models was estimated to be between 7.2% and 7.7% of the maximum instantaneous WSS and reproducibility comparing the three scans to be between 8.2% and 10.7% of their average maximum.
引用
收藏
页码:218 / 222
页数:5
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