The role of virtual screening in computer aided structure-based drug design

被引：11

作者：

Branson, KM ^{[1
]}

Smith, BJ ^{[1
]}

机构：

[1] Royal Melbourne Hosp, Walter & Eliza Hall Inst Med Res, Struct Biol Div, Parkville, Vic 3050, Australia

来源：

AUSTRALIAN JOURNAL OF CHEMISTRY | 2004年 / 57卷 / 11期

关键词：

D O I：

10.1071/CH04161

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The pharmaceutical industry has embraced computational methods to improve the successful negotiation of hits and leads into drugs in the clinic. This review examines the current status of in silico screening methods and aspects of compound library design.

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收藏

页码：1029 / 1037

页数：9

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