Boron trifluoride-mediated alkylation of diphenylphosphine with tert-alkyl fluoride

被引：36

作者：

Hirano, K ^{[1
]}

Yorimitsu, H ^{[1
]}

Oshima, K ^{[1
]}

机构：

[1] Kyoto Univ, Grad Sch Engn, Dept Chem Mat, Nishikyo Ku, Kyoto 6158510, Japan

来源：

ORGANIC LETTERS | 2004年 / 6卷 / 26期

关键词：

D O I：

10.1021/ol048069p

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[Graphic] Treatment of tertiary alkyl fluoride with diphenylphosphine in the presence of a stoichiometric amount of boron trifluoride etherate yields the corresponding tert-alkyldiphenylphosphine despite the coexistence of the strong Lewis acid and the highly coordinating phosphine. Use of diphenyl(trimethylsilyl)phosphine as a nucleophile makes the reaction catalytic in boron trifluoride.

引用

页码：4873 / 4875

页数：3

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