Heritability of poor language achievement among twins

被引:121
作者
Tomblin, JB [1 ]
Buckwalter, PR [1 ]
机构
[1] Univ Iowa, Dept Speech Pathol & Audiol, Iowa City, IA 52242 USA
来源
JOURNAL OF SPEECH LANGUAGE AND HEARING RESEARCH | 1998年 / 41卷 / 01期
关键词
language disorders; children; heritability; twins;
D O I
10.1044/jslhr.4101.188
中图分类号
R36 [病理学]; R76 [耳鼻咽喉科学];
学科分类号
100104 ; 100213 ;
摘要
In order to examine the basis of Familial associations with poor language achievement, 62 twinship pairs and 3 sets of triplets were studied in which at least one member presented poor oral language status in the absence of other developmental or sensory impairments. Rates of concordance for poor language were compared between the monozygotic (MZ) and dizygotic (DZ) pairs. Concordance for the MZ pairs was .96, whereas it was .69 for the DZ pairs. The DeFries-Fulker method for computing heritability of extreme scores was employed yielding a h(g)(2) of .45. Similar results were obtained for those pairs containing only children with performance IQs above 85, but with at least one member having language below -1 SD. A comparison of DZ twins with singleton sibling pairs with at least one affected member and of similar age showed that DZ twins were more similar with respect to language achievement than singleton pairs. Thus, twinning appeared to have influenced twin resemblance among those where at lead one member presented poor language achievement. These results support the hypothesis that genetic factors contribute to the liability of poor language achievement in children who do not present other developmental or sensory disorders.
引用
收藏
页码:188 / 199
页数:12
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