1,4-hydrogen radical transfer as a new and versatile tool for the synthesis of enantiomerically pure 1,2,3-triols

被引：37

作者：

Gulea, M ^{[1
]}

López-Romero, JM ^{[1
]}

Fensterbank, L ^{[1
]}

Malacria, M ^{[1
]}

机构：

[1] Univ Paris 06, CNRS, Lab Chim Organ Synth, F-75252 Paris 05, France

来源：

ORGANIC LETTERS | 2000年 / 2卷 / 17期

关键词：

D O I：

10.1021/ol000133p

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] 1,4-Hydrogen radical transfers can now be reliably envisaged in radical synthetic chemistry as demonstrated by the formation of the cyano derivative II from I. Due to related sequences involving this new translocation process, followed by a highly diastereoselective trapping of the resulting anomeric radical, access to intriguing enantiopure 1,2,3-triols such as III is available.

引用

页码：2591 / 2594

页数：4

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