Probing exosome internalization pathways through confocal microscopy imaging

被引：25

作者：

He, Fang ^{[1
]}

Ye, Ze-Yu ^{[1
]}

Zhao, Li-Dong ^{[1
]}

Yin, Bin-Cheng ^{[1
,2
,3
]}

Ye, Bang-Ce ^{[1
,2
,3
]}

机构：

[1] East China Univ Sci & Technol, State Key Lab Bioreactor Engn, Lab Biosyst & Microanal, Shanghai 200237, Peoples R China

[2] Zhejiang Univ Technol, Coll Pharmaceut Sci, Collaborat Innovat Ctr Yangtze River Delta Reg Gr, Inst Engn Biol & Hlth, Hangzhou 310014, Zhejiang, Peoples R China

[3] Shihezi Univ, Sch Chem & Chem Engn, Xinjiang 832000, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2019年 / 55卷 / 93期

基金：

中国国家自然科学基金;

关键词：

EXTRACELLULAR VESICLES; CELL;

D O I：

10.1039/c9cc07491k

中图分类号：

O6 [化学];

学科分类号：

070301 [无机化学];

摘要：

We developed a novel fluorescence labelling method to track exosome internalization pathways in cells by confocal microscopy. The proposed method allows evaluation and comparison of the uptake pathways of exosomes originating from different cells, which would offer the potential for understanding the functions of exosomes in intercellular communication and their applications in drug delivery.

引用

收藏

页码：14015 / 14018

页数：4

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