Synthesis of two conformationally constrained analogues of the minor tobacco alkaloid anabasine

被引：51

作者：

Lindström, S ^{[1
]}

Ripa, L ^{[1
]}

Hallberg, A ^{[1
]}

机构：

[1] Univ Uppsala, BMC, Dept Organ Pharmaceut Chem, SE-75123 Uppsala, Sweden

来源：

ORGANIC LETTERS | 2000年 / 2卷 / 15期

关键词：

D O I：

10.1021/ol006056f

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] The anabasine analogues spiro[4-azaindan-1,2'-piperidine] (7) and spiro[6-azaindan-1,2'-piperidine] (8) have been prepared. A series of palladium-catalyzed reactions, where an intramolecular cyclization constituted a key reaction, were utilized for the preparation of the two target compounds.

引用

页码：2291 / 2293

页数：3

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