Cancer gene therapy: Fringe or cutting edge?

被引：280

作者：

McCormick, F ^{[1
]}

机构：

[1] Univ Calif San Francisco, Inst Canc Res, San Francisco, CA 94115 USA

来源：

NATURE REVIEWS CANCER | 2001年 / 1卷 / 02期

关键词：

D O I：

10.1038/35101008

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Direct targeting of cancer cells with gene therapy has the potential to treat cancer on the basis of its molecular characteristics. But although laboratory results have been extremely encouraging, many practical obstacles need to be overcome before gene therapy can fulfil its goals in the clinic. These issues are not trivial, but seem less formidable than the challenge of killing cancers selectively and rationally - a challenge that has been successfully addressed.

引用

页码：130 / 141

页数：12

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